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Arterioscler Thromb Vasc Biol 26:481487 Liu T, Deng K, Xue Y, Yang R, Yang R, Gong Z, Tang M (2022) Carnitine and depression

46 In a simulative binding model of GIP and the receptor, the fragment from position 3142 neither interacted with the receptor, nor formed any specific structure, but it was able to cling to the receptor

More importantly, the magnitude of improvement in body weight resulted from increased energy expenditure and decreased food intake, which led to a remarkable loss of fat mass

The rationale for combining these two agents is deeply rooted in the complementary biology described above

J Biol Chem (2015) 290:553342

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