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A total of 36 patients who received at least one dose of study medication (10 in the semaglutide group, 26 in the metformin group) and had at least one post-baseline assessment, were included in the efficacy analyses (Fig
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Oral Semaglutide Because the gut is a challenging environment for absorption, oral semaglutide doses are much higher 25 milligrams (mg) daily than standard 2.4-mg weekly injections
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[8] [9] This metabolic conflict could reduce the efficacy of tirzepatide, necessitating closer monitoring and potentially increasing the risk of hyperglycaemia
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