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Older medications like phentermine-topiramate (Qsymia) or naltrexone-bupropion (Contrave) work differently, targeting neurotransmitters in the brain rather than gut hormones

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Combining GLP-1 medications and phentermine can enhance appetite control, boost energy levels, and potentially lead to greater weight loss compared to using either medication alone

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Low blood sugar can happen more often when XIGDUO XR is taken with certain other diabetes medicines