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Comparing the actual trial data, rather than the marketing claims built on top of it, is the clearest way to answer the does AOD-9604 work question directly
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doi: 10.1016/j.jdiacomp.2012.12.007 179 ZayaniYAllal-ElasmiMJacobMPZidiWFtouhiBFekiMet al
The titration regimen described in the NEJM 2023 obesity trial (Jastreboff et al.) progressed as follows: Weeks 14 : 2 mg once weekly Weeks 58 : 4 mg once weekly Weeks 912 : 8 mg once weekly Week 12 onwards : Up to 12 mg once weekly (in higher-dose cohorts) This regimen was used exclusively within a regulated clinical trial setting and does not constitute an approved dosing schedule
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