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The 1 MHz FUS stimulation was delivered to DVC (AP = -7.00 mm, ML = 0.30 mm, DV = -5.70 mm) with following parameters: 550 kPa peak rarefactional pressure, 10 Hz pulse repetition frequency, 10% duty cycle and duration for 2 min

Low-dose naltrexone for primary progressive multiple sclerosis: a placebo-controlled, double-blind, randomized controlled trial

The analysis focused on 22 neurological and psychiatric outcomes, including cognitive deficits, dementia, parkinsonism, psychosis, and substance misuse

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Inflammation and peripheral nerve injury increase NGF expression and sensitise peripheral nociceptive terminals through the induction of gene expression in nociceptors [28]

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