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When stool sits in the colon longer than usual, it dries out and gets harder to pass

The reason it's not listed is that it's not a direct result of the medication

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Both of these medications can be expensive without insurance coverage

Obesity-Induced Lymphedema Some people develop lymphedema from severe, long-term obesity rather than cancer treatment or other causes

Clinical guidelines support escalating from 0.25 mg up to 2.4 mg weekly based on response and tolerability