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It can cause some gastrointestinal symptoms, but you will most likely be able to mitigate these with a lower prescribed dosage

Others, like Sarah, find that switching medications due to cost or availability unexpectedly triggers a stall

4 "Across TRIUMPH-1 and TRANSCEND-T2D-1, retatrutide delivered substantial weight loss, meaningful A1C reduction, and improvements in knee osteoarthritis pain and moderate-to-severe obstructive sleep apnea, a breadth and magnitude of outcomes that's striking to see with a single therapy," said Kenneth Custer, Ph.D., executive vice president and president, Lilly Cardiometabolic Health

For patients comparing options in the GLP-1 family, our tirzepatide 3-month weight loss guide can help set realistic expectations about progress over time