It does this by reducing appetite and slowing down how quickly food leaves the stomach
The medication also has contraindications for those with known hypersensitivity to tirzepatide or its excipients
Potential side effects of GLP-1 agonists include nausea, vomiting, diarrhea, dizziness, mild tachycardia, and headaches
For weight management in the UK, NICE-approved options are limited to orlistat (available over-the-counter or on prescription) and, within specialist weight management services, liraglutide 3.0mg (Saxenda) or semaglutide 2.4mg (Wegovy) with their specific continuation criteria
263,264 Apart from intracellular antioxidants like glutathione (GSH), heme oxygenase-1 (HO-1), superoxide dismutase-1, and nicotinamide adenine dinucleotide phosphate (NAPDH), MTs also serve as a redox buffer by interacting with and scavenging reactive species
According to FDA prescribing information, the most common side effects include nausea, vomiting, diarrhea, and constipation, particularly during dose escalation