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Plasma GHK-Cu levels start dropping measurably around age 25, the same age you begin losing roughly 1% of your collagen per year

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References Chatterjee A

Endothelial cells play a fundamental role in chronic oxidative stress and the development of atherosclerosis, thrombosis and lung injury, principal complications of SARS-CoV-2-mediated tissue and organ dysfunction (Chang et al., 2021)