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Some people need a short course close together, while others may only need occasional top-ups for maintenance

Intramuscular: 500 mcg near the injury site for localized effect

Instead, take it with cold water, milk, or a smoothie

The AAFPs evidence-based clinical review states directly: Oral administration of high-dose vitamin B12 (1 to 2 mg daily) is as effective as intramuscular administration for correcting anemia and neurologic symptoms in patients with B12 deficiency (Langan RC, Goodbred AJ, American Family Physician, 2017)

Numerous studies have shown that GSH anabolism and GPX4 are inextricably linked to ferroptosis

Without direct tissue quantification, it is unknown if the CNS exposure was high, or if the large systemic dose simply compensated for low anatomical delivery efficiency across the nasal mucosa