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Zepbound (tirzepatide) is a novel glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA in November 2023 for chronic weight management in adults with obesity or overweight with weight-related comorbidities
As mentioned, trials focusing on GLP-1 RA treatment in HFrEF are few and of a smaller scale
It is not for everyone, and it requires working with a healthcare provider who is open to non-standard dosing strategies
Apart from red blood cells, which tissues would you expect to have a high activity of the pentose phosphate pathway
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