The drugs reduce hunger, while tracking, coaching, and community support build long-term habits
Thus, any comparison must be based on existing data from liraglutide's phase 3 trials and retatrutide's phase 2 trials: According to a 2016 systematic review of 43 randomized trials, liraglutide has shown significant benefits for T2D, with doses ranging from 1.2-1.8mg/daily leading to HbA1c decreases between -0.9% and -2.2% over six months
Older adults, in particular, face an increased risk of falls, broken bones and hospital stays when they lose the muscles they need to keep stable
Two points deserve emphasis
Which one would you want? Obesity is a complex pathophysiologic disease and under both homeostatic and hedonic control, says Amy E
Retatrutide has the highest overall adverse event burden, primarily because of the dysesthesia issue