However, healthy individuals synthesise glutathione endogenously at rates sufficient to meet this demand if dietary intake of cysteine, glutamate, and glycine is adequate
While we used several markers (including SA--gal, lipofuscin, cyclin-dependent kinase inhibitors, SASP components and transcriptional senescence signatures) to characterize senescence in these models, we have to acknowledge the limitations of our study given the inherent heterogeneity of senescent cells
For studies of IGF1R signaling itself, that is a feature, not a limitation
Glutathione regulates 1-aminocyclopropane-1-carboxylate synthase transcription via WRKY33 and 1-aminocyclopropane-1-carboxylate oxidase by modulating messenger RNA stability to induce ethylene synthesis during stress
LncRNA PVT1 promotes proliferation and invasion through enhancing Smad3 expression by sponging mir-140-5p in cervical cancer
Diabetes 53, 20672072