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The adverse events, particularly GI events, mostly occurred during the dose-escalation phase of the trial, said Aronne
Discussion In this study, we conducted a real-world assessment of GLP-1 efficacy over 12 months among US adults as compared to a matched set of controls who were clinically similar but likely pursued other therapeutic options to manage their weight and HbA1c
Kulbacka J, Saczko J, Chwikowska A
Cochrane Database Syst Rev 2012;cd007543
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These observations are consistent with, though do not prove, a role for oxidative stress in migraine pathophysiology, and are discussed below in the context of existing literature and the limitations of the present sample size
