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These results are the basis for a positioning of the DPP-4 inhibitors as second-line therapy for the treatment of type 2 diabetes, especially, when hypoglycaemia should strictly be avoided (see section below)

10.1016/j.androl.2020.01.009 55 OhkawaH.OhishiN.YagiK

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The third compound, 5-Amino-1MQ, influences how efficiently NAD+ precursors are used by the body

BMC Syst Biol 7:103 Liu B, Teschemacher AG, Kasparov S (2017) Astroglia as a cellular target for neuroprotection and treatment of neuro-psychiatric disorders