Foundayo (orforglipron) is a once-daily weight-loss pill manufactured by Eli Lilly that received FDA approval just this past April 1, 2026
Moreover, small reductions in body weight alone can have beneficial effects on blood pressure as well as glucose and cholesterol metabolism (Klein et al., 2004
Feng et al., 2022) (Table 1)
Drug manufacturers have developed dual and triple agonists for the modulation of several metabolic pathways, which are intended to improve blood sugar levels and facilitate weight loss
A multicenter, placebo-controlled trial in MCI and AD patients confirmed that vitamin E supplementation reduces LPO and delays progression from MCI to AD (315)
If those diseases have intact neurons, and components of the eye, and the structure is largely intact, then I would be optimistic that we could make those cells function well again