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Whereas peripheral factors from the gastrointestinal system are known to exert influence on homeostatic feeding areas, such as the brainstemhypothalamic circuit, there is evidence that they can alsodirectly or indirectlyinfluence the brains reward system (Klockars et al., 2021

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Semaglutide Effects on Cardiovascular Outcomes in People With Overweight or Obesity , [Online] (2023)

Semaglutide reduces A1c by 1.0 to 1.5 percentage points on average