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A broad panel of antibodies was employed, including those for FOXO4, p53, phospho-p53, p21, p16, cleaved-Caspase3, BAX, BCL-2, testosterone synthesis enzymes (3-HSD, CYP11A1, CYP17A1), and various SASP factors (IL-1, IL-6, TNF-, TGF-)

International Journal of Cosmetic Science, 27 (3), 155-160

Delivery technology innovations Nanoparticle formulations: Encapsulating peptides in biodegradable nanoparticles protects from degradation, enhances tissue penetration, provides sustained release

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That has been part of the standard response when Ive shared this stuff for over a decade now

A: BAC water's 0.9% benzyl alcohol prevents bacterial growth allowing multi-dose use over days to weeks