Without an intentional eating strategy, many people on GLP-1s lose not just fat, but also muscle, energy, and digestive regularity
Storage is refrigerated
One advantage of synthetic GLP-1 drugs like Ozempic or Wegovy is their prolonged presence in the body compared to naturally occurring GLP-1
Abbreviations ARB: Angiotensin receptor blocker CKD: Chronic kidney disease CRP: C-reactive protein DKA: Diabetic ketoacidosis DKD: Diabetic kidney disease ERA: Endothelin receptor antagonist ESKD: End-stage kidney disease GIP: Glucose-dependent insulinotropic polypeptide GLP1: Glucagon-like peptide 1 GLP1-RA: Glucagon-like peptide 1 receptor agonist HF: Heart failure hsCRP: High-sensitivity C-reactive protein MACE: Major adverse cardiovascular events MRA: Mineralocorticoid receptor antagonist NO: Nitric oxide RAS: Reninangiotensin system sGC: Soluble guanylate cyclase SGLT2i: Sodiumglucose cotransporter-2 inhibitor(s) UACR: Urine albumin to creatinine ratio References Rossing P, Caramori ML, Chan JCH et al (2022) KDIGO 2022 clinical practice guideline for diabetes management in chronic kidney disease

Many patients taking GLP-1 receptor agonists for type 2 diabetes or weight management wonder whether these medications might improve cognitive symptoms like difficulty concentrating, memory problems, and mental fatigue
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