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However, if the pain worsens after 1014 days, swelling doesnt improve, or they experience redness, warmth, fever, or signs of infection, patients should seek medical attention

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The sequence consists of 15 amino acids: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val

Patients require evaluation before starting DMARDs to rule out contraindications to the medications (meaning the patient should not take a certain medication due to the harm it would cause) and monitoring while using them to watch for serious side effects

The lyophilised protein remains stable until expiry date when stored at -20c

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