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Glucagon Receptor: Stimulates fat oxidation, increases energy expenditure, and reduces liver fat stores

Being overweight or obese leads to a build-up of visceral fat a type of fat that wraps around the organs and increases the risk of conditions such as heart disease and diabetes which triggers inflammation, creating an environment for cells to multiply uncontrollably

Mechanistic and translational studies suggest that the underlying metabolic dysregulation in patients with obesity, particularly hyperglycemia and insulin resistance, contributes to altered immune cell function and low-grade systemic inflammation

Semaglutide 2.4 mg weekly can produce ~1520% body weight reduction over 68 weeks ( [11] )

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Garzon S, Apostolopoulos V, Stojanovska L, Ferrari F, Mathyk BA, Lagana AS