Alcohol can impair liver function regardless of GLP-1 therapy, and excessive intake remains a known risk factor for liver injury
John Swann: She used her own name, uh, explained that she wanted to lose a few pounds, even though she herself was, stood 55 and weighed 123 pounds
However, the EMA advises against using liraglutide and semaglutide in individuals with a creatinine clearance below 30 mL/min, which corresponds to CKD stages 4 and 5 or kidney failure
These side effects are generally mild to moderate and usually go away within a few weeks
Millions of patients are now using these medications, so its conceivable a rare, previously unidentified side effect may appear, but overall, the concern is low that something new or unusual will emerge, McGowan says
In direct trials, it notably outperformed injectable semaglutide (Ozempic)