It is not an FDA-approved drug for systemic therapeutic use
PubMed laboratory research record [PMID: 4724072] PubMed record related to this compound for laboratory literature review
NCTC1469 cells, a normal mouse hepatocyte cell line, were obtained from the American Type Culture Collection and were cultured in DMEM containing 10% (v/v) fetal horse serum, 2 mM glutamine, 5 U/mL penicillin, and 50 g/mL streptomycin at 37 C in a humidified O 2 /CO 2 (19:1) atmosphere
5-Amino-1MQ is a synthetic compound currently being studied for its interaction with an enzyme called NNMT (nicotinamide N-methyltransferase)
This observation is conceptually important because it argues against the view that ferroptotic spread is merely a pathological by-product of tissue injury
Data & Methodology Results come from a May 2026 online survey of 2,491 U.S