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Across the cagrilintide clinical program, the dominant tolerability issues have been gastrointestinal: nausea, reduced appetite, constipation, and, less commonly, vomiting a profile shared with pramlintide and with GLP-1 agonists, and mechanistically expected from a compound that slows the stomach and engages the area postrema

The HPLC trace for BPC-157, the HPLC trace for TB-500, the dual-target mass spectrum, and the endotoxin reading all sit under a single lot identifier with no repackaging steps obscuring the chain of custody

BPC-157 is a different category of approach

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Hepatology 56 , 21992208 (2012)