The brand states that taking two or three capsules is "safe, but unnecessary." This article did not independently verify that higher-dose safety claim, and you should follow the labeled serving directions unless a healthcare professional advises otherwise
The regulation of NSC proliferation, self-renewal, and differentiation is finely regulated by changes in the surrounding microenvironment, or niche, in which NSCs reside (reviewed in Andreotti et al., 2019)
The bone receptors may affect bone formation and turnover
Rather than jumping to the maximum dose as quickly as the prescribing guidelines allow, consider staying at each dose level for a longer period
Problems with blood or blood vessels
Some patients notice constipation during dose escalation phases, whilst others develop more persistent symptoms