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Specifically, these structures are termed circumventricular organs, and act to receive signals from circulation, like angiotensin II (Ang II), nitric oxide (NO), atrial natriuretic peptide (ANP), vasopressin (AVP), and endothelin
Meanwhile, either when using UKPDS 68 risk equations, or when altering utility impacts [27, 28] or halving costs for vascular complications, the resulted QALY and cost outcomes remained similar to that in base case
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