Hausswirth C, Bigard AX, Lepers R, et al
8, 16087 doi: 10.1038/ncomms16087 (2017)
As with any supplement, it is advisable to consult a healthcare professional before beginning a new regimen to ensure it is appropriate for individual health needs and to discuss any potential interactions or contraindications.
Lyophilized powder that has yellowed or clumped may have been exposed to heat or moisture
Among them, IGF/IGF-1R signals can improve radiotherapy sensitivity by activating a series of signal transduction events involved in DNA damage repair

Abbreviations ACADS : Short-chain specific acyl-CoA dehydrogenases ACOX : Acyl-coenzyme A oxidese ACSS : Acyl-CoA synthetase short-chain family ALDOC : Aldolase C BEX2 : Brain expressed X-linked 2 BRD4 : Bromodomain-containing protein 4 BRD9 : Bromodomain-containing protein 9 CALM3 : Calmodulin like protein 3 CAMs : Cell adhesion molecules CBP : CREB-binding protein CDYL : Chromodomain Y-like CRC : Colorectal cancer DGCs : Differentiated glioblastoma cells DPF : Double PHD zinc finger dsRNA : Double-stranded RNA ECHS1 : Enoyl-CoA hydratase ENO1 : Enolase 1 ENO2 : Enolase 2 ETS1 : E26 transformation-specific 1 GBM : Glioblastoma GCDH : Glutaryl CoA dehydrogenase GCN5 : General Control Non-derepressible 5 GSCs : Glioblastoma stem cells GSH : Glutathione HATs : Histone acetyltransferases HCC : Hepatocellular carcinoma HCTs : Histone crotonyltransferases HDAC : Histone deacetylases hMOF : Human MOF HNRNPA1 : Heterothymic nuclear ribonucleoprotein A1 HSP90AB1 : Human heat shock protein 90 alpha family class B member 1 Kbhb : -Hydroxybutyrylation Kbu : Butyrylation Kbz : Benzoylation Kcr : Crotonylation Kcr : Lysine crotonylation Kglu : Glutarylation Kla : Lactylation Kpr : Propionylation Ksucc : Succinylation LNCaP : Lymph node carcinoma of the prostate MCM6 : Minichromosome maintenance 6 MTHFD1 : Methylenetetrahydrofolate reductase NDP52 : Nuclear domain 10 protein 52 NEAT1 : Nuclear enriched abundant transcript 1 NSCLC : Non-Small cell lung cancer NSCs : Neural stem cells OSCC : Oral squamous cell carcinoma PCa : Prostate cancer PCAF : P300/CBP-Associated Factor PDAC : Pancreatic ductal adenocarcinoma PDH : Pyruvate dehydrogenase PDHK1 : Pyruvate dehydrogenase kinase isoform 1 PGD : 6-Phosphogluconate dehydrogenase PGK1 : Phosphoglycerate kinase 1 PKA : Protein kinase A PPP : Pentose phosphate pathway PRKACA : Proteins closely related to protein kinase A PTBP1 : Polypyrimidine tract-binding protein 1 PTMs : Post-translational modification RRM2 : Resistance-related genes 2 SASP : Senescence-associated secretory phenotype SEPT2 : Septin2 SIRT : Sirtuin SLC7A2 : Solute carrier family 7 member 2 TAF1 : TBP-Associated Factor 1 TEs : Transposable elements TKT : Transketolase TSS : Transcription start sites References Aghdassi A, Sendler M, Guenther A, Mayerle J, Behn C-O, Heidecke C-D, et al
