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Loren Pickart estimated the lethal dose at approximately 22,500 mg for humans, which is 300-fold above effective doses
In those with serious events, risk factors for bleeding were often present, or patients were taking other drugs that cause thrombocytopenia or affect platelet function or coagulation
It also elevated the level of antioxidant enzymes
Future research should focus on validating these approaches and exploring new avenues for the effective treatment of PACS
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