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Allosteric inhibition of hypoxia inducible factor-2 with small molecules

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Available online at: 146 WangY.WisniewskiM.MeilanR.CuiM.WebbR.FuchigamiL

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In addition to GSH inhibition, LCS3 is reported to inhibit the activity of thioredoxin reductase1 (TXNRD1), a critical antioxidant regulator maintaining the redox state of thioredoxin (TRX) [19](Supplementary Fig

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