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Kaynak: Rathi A, et al

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The Liver-selective TR knockout mice (LTRKO) were generated by cross-breeding of TR Floxed mice with mice harboring Cre-recombinase under the control of the albumin promoter (Alb-Cre mice)

Initial changes like improved skin hydration often appear within 2-4 weeks

Weight change was estimated using Bayesian latent growth-curve models with 95% credible intervals reported

The list of potential benefits of GLP-1 drugs is only getting longer, with a new review of mostly preclinical studies linking these popular diabetes and weight-loss medications to limiting the molecular hallmarks of dementia