Research shows treated animals lost an average 5.1% body weight, 30% reduction in adipocyte size and 35% decrease in white adipose tissue mass
1990 Oct;259(4 Pt 1):G524-9
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To confirm this, we treated HUVECs with the proteasome inhibitor MG132 and the protein synthesis inhibitor cycloheximide (CHX, 10 g/mL)
Biol Psychiatry 97:11271138
Hum Psychopharmacol Clin Exp 10:S107S118 Delbressine L, Moonen M, Kaspersen F, Wagenaars G, Jacobs P, Timmer C, Paanakker J, Van Hal H, Voortman G (1998) Pharmacokinetics and biotransformation of mirtazapine in human volunteers