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When GLP-1R is activated, microglial activation is suppressed, reducing the levels of VEGF and other cytokines involved in neovascularization

Inadequate protein intake leads to muscle loss, which further reduces metabolic rate

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If vomiting has already occurred, it is not thought that gastric lavage would be of further benefit

Melanotan I is a synthetic linear analogue of alpha-melanocyte-stimulating hormone (-MSH) that binds to melanocortin receptors (primarily MC1R) to stimulate melanin production

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