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Several features of ferroptosis include oxidative burst, particularly increased lipid peroxidation and this cell death program can be readily prevented by a specific ferroptosis inhibitor, ferrostatin-1 (Fer-1) 19

Rat islet isolation and culture Islets were harvested from SpragueDawley rats (~ 250 g) that were anesthetized by an intraperitoneal injection of pentobarbital sodium (150 mg/kg)