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Buffered NAD+ ships with a pH stabilizer (most commonly Tris) that brings the reconstituted solution closer to physiological pH (~7-8.5), while unbuffered NAD+ reconstitutes acidic (~pH 3-4) and is more often associated with injection-site stinging
for the related NAD+ research thread, see NAD+ and Sirtuins
Obesity specialist Spencer Nadolsky, D.O., on the other hand, had a very different experience with the same peptide
Can NAD+ support athletic performance and recovery
Precautions Do not use B12/MIC if you are pregnant, nursing, or planning to become pregnant or breastfeed
This stability has made it valuable for studying gastrointestinal function, connective tissue biology, and regenerative processes
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