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Chalasani N, Abdelmalek MF, Garcia-Tsao G, et al

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Regarding macrovascular complications, comparable incidence of myocardial infarction was observed between patients receiving SGLT2i and GLP1-RA, which was consistent with a population-based cohort study [37]

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These findings highlight the urgent need for evidence-based guidance for when GLP-1RAs should be used relative to bariatric surgery in adolescents and young adults, including whether medications are most effective before surgery, after surgery, or as part of combination therapy. Other UTSW researchers who contributed to this study are senior author Sarah Barlow, M.D., M.P.H., Professor of Pediatrics

SMD, Standardized mean difference