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But the fundamental limitation remains: phentermine effectiveness plateaus and often declines over time as the body adapts to the stimulant effect
Either the manufacturer can supply or they cant and FDA uses this shortage list to try to inform and to allow for supply outside of the normal approval process, said the former FDA investigations branch director
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Patients who titrate aggressively (low to max dose in 16-20 weeks) usually end the first year at a higher average than patients who slow-walk titration
The concerns often stem from prior animal studies that revealed a link between the medications and abnormal alterations in thyroid C cells
PMID 7882173
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