The analysis of the frequency in FA esterified TGs and DGs showed, 16:00, 18:00, 18:01 were top three highest frequency in upregulated TGs (Supplementary Figure 3D), while 18:01 was highest frequency in upregulated DGs (Supplementary Figure 3E)
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Post hoc, the Semaglutide Effects on Cardiovascular Outcomes in People with Overweight or Obesity (SELECT) trial, which was the first to assess GLP-1 receptor agonists in participants without diabetes, was incorporated into the analysis
As with any medication, there are risks associated with using GLP-1s, and much of that risk depends on an individuals health history
Additionally, tolerability of the regimen remains a question
Source Data are provided in Source Data