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Neuropsychopharmacology 36(11):23572367 Alexander KS et al (2012) Acute elevations of brain kynurenic acid impair cognitive flexibility: normalization by the alpha7 positive modulator galantamine

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No matter what weve done, weve not been able to nail precisely why they are resistant. Unexpected resistance The researchers focused on two variants that disrupt an enzyme called PAM (peptidyl-glycine alpha-amidating monooxygenase), which activates several hormones, including GLP-1

Journal of Strength and Conditioning Research 28(2):p 514-519, February 2014

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