The sweet spot for most trials is between 3g and 6g daily, with or without a loading phase (5-10 days of higher creatine intake before reducing to around 3-6g daily).2 3 Some studies even use 10g of creatine, showing both muscle-building effects and the ability to improve cognition and general wellness.4 5 Those are pretty large doses, which is why so many creatine supplements are sold in powder form instead of as capsules
However, after 1 outlier SNP was eliminated by MR-PRESSO, the statistical significance of albumin on AD diminished (OR = 1.134, p = 0.056)
Specifically in regard to nausea, it tended to be most pronounced in the first 4 weeks of therapy in all phase III LEAD trials, with symptoms generally dissipating over the remainder of the study period
Individual response depends on dose and duration, but also on zinc, glutathione, protein intake, mitochondrial reserve, liver metabolism, kidney filtration, bowel elimination, gut health and methylation
L-carnitine and D-carnitine isomers exist in mammals
Melanie Avalon I'm going to ask for that for dessert