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Potential Side Effects and Precautions While methylcobalamin injection is generally considered safe, some people might experience minor side effects, such as: Pain or redness at the injection site Mild diarrhea Headache or nausea Rare allergic reactions In patients with kidney issues or those on certain medications, methylcobalamin must be used cautiously
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This is more likely when B12 is given in injectable form rather than taken orally
Cyanocobalamin is primarily prescribed for vitamin B12 deficiency, which can occur due to a variety of conditions such as pernicious anemia, prolonged use of certain medications, surgery in the gastrointestinal tract or dietary deficiencies