[Article] [PubMed] [PMC]39
At physiological pH, H 2 S (pKa ~7) exists predominantly (~70%) as the hydrosulfide anion (HS ) while the conjugate acid freely diffuses through biological membranes to access the catabolic machinery within mitochondria 4
Additional information Handling Author: Pramod Kumar Nagar Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations
Li L, Li WJ, Zheng XR, Liu QL, Du Q, Lai YJ, et al
10.1021/acsbiomaterials.2c00023 72 MaX.FengY.WangT.LeiW.LiX.ZhouD.et al (2017)
Although hydroxyurea is currently the most affordable and available treatment, it does not cover all SCD patients