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Although the within-group reduction in the ASV + NAC group did not reach statistical significance, the comparison between groups revealed a significant improvement in oxidative balance, favoring the ASV + NAC regimen (U = 57, P = 0.021)

At 2000mg/kg, severe toxicity behaviors were observed characterized by the above-mentioned effects with additional loss of a righting reflex, unusual vocalization, hyperventilation, writhing, convulsions and ultimately death of two animals

It is unclear whether the last bout of exercise was necessary to observe these effects or if the end-of-training baseline samples were endowed with similar cargo

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