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Koi's Canadian production partner assembles the chain by Fmoc solid-phase chemistry, attaches the trans-3-hexenoyl group at the N-terminal tyrosine, and finishes with C-terminal amidation during cleavage
PMID: 21030672 | doi:10.1152/japplphysiol.00945.2010 Zivanovic-Posilovic G et al
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The distinction matters when considering the research required to validate any of them
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