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If sleep issues persist beyond the adaptation phase, melatonin becomes a reasonable next step
Unlike weekly GLP-1 injections, Saxenda requires daily administration
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doi:10.1016/j.ejps.2017.03.020 29
Retatrutide combines agonism of GIP, GLP-1, and Glucagon receptors in a single molecule, a physiological strategy that researchers believe can unlock even greater metabolic potential
One possible explanation is that both caffeine and GLP-1s interact with dopamine, our reward chemical, in the brain
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