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51 Studies of dogs with osteoarthritis have shown that treatment with PEA plus quercetin, at a daily dose of 24 mg/kg body weight for four weeks, or a PEA derivative called palmitoyl-glucosamine plus curcumin for 12 months led to improvements in dog mobility and function and reductions in pain and lameness

E.ZhouJ

The only study was conducted on rats and explicitly states it cannot guide human dosing

Mol Pharm (2007) 4:80718

In recent years, researchers have focused on understanding the mechanisms of multidrug resistance (MDR) in cancer cells and have identified the overexpression of ATP-binding cassette (ABC) transporters, including ABCC1/MRP1 and ABCC10/MRP7, as a key factor in the development of MDR

Otto, T