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What You Need Reconstituted retatrutide vial or pen device Appropriate insulin syringe if drawing from a vial (see the retatrutide reconstitution guide for mixing steps) Alcohol swabs Sharps disposal container Optional: gauze or cotton ball for post-injection pressure Site Prep Steps Choose your site for this week from one of the 3 DailyMed-approved zones, rotating from last week's location Clean with an alcohol swab and allow the site to dry for 10 to 15 seconds before injecting (DailyMed label: "Clean the injection site with alcohol before injection") Pinch the skin gently if adequate subcutaneous fat is present, per MSKCC subcutaneous injection guidance Insert the needle at a 45 to 90 degree angle depending on needle length and tissue depth (shorter needles use 90 degrees

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Administering Tirzepatide Tirzepatide involves once-weekly injections, rotating sites like the abdomen, thigh, or upper arm to form a routine