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Abstract Purpose of Review This review summarizes the current understanding of the physiologic influence of GLP-1 RAs on gastrointestinal motility, highlights key clinical implications of these effects, and defines areas for future investigation
But despite their explosive demand, GLP-1s have their share of drawbacks
Benefits of GLP-1s Beyond Weight Loss and Diabetes Why Research on GLP-1s and Cancer Deserves Attention Real-world studies presented at medical conferences this year including one organized by ASCO (the American Society of Clinical Oncology) have scientists feeling energized to further investigate the impact of GLP-1s on cancer
Biochemical changes : Caused significant liver damage and necrosis of cells as evidenced by the elevated serum hepatic enzymes ALT, AST, ALP, and GT
avoid on dose-increase days
These lower doses were not part of the studies that led to FDA approval
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