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J Clin Invest 91(1):301307
Effectiveness: In a study of 2,539 adults with obesity or overweight plus at least one weight-related medical condition (excluding diabetes), the average weight loss at 72 weeks was 15% with 5 mg weekly doses of tirzepatide, 19.5% with 10 mg doses, and almost 21% with 15 mg doses
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Caffeine remains the world's most widely used and evidence-backed nootropic, reliably improving alertness, reaction time, and short-term memory when used in controlled amounts
1 Obesity rates are also climbing
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