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In placebo-controlled trials, severe GI reactions were reported in 1.7% (5 mg), 2.5% (10 mg), and 3.1% (15 mg) of Zepbound-treated patients compared to 1% of placebo-treated patients

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doi: 10.1517/14656566.2014.965678 58 AndersonSLTrujilloJM

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The study, published in November in the New England Journal of Medicine, found that patients who took the medication had lower rates of significant heart events like heart attack and stroke than patients who took a placebo

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