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This creates a clinical flow where patients initiate on oral therapy, stabilize, and either remain on pills or step up to higher-efficacy injectables based on their clinical needs, a tiered treatment model that expands the overall market rather than simply redistributing it

Metabolic adjustment Semaglutide changes how quickly food moves through the digestive system and how hormones signal fullness

These medications mimic natural GLP-1, a naturally occurring hormone produced by the body that plays a crucial role in how our bodies regulate blood sugar and appetite

Variants in genes encoding GLP-1 receptor, GIPR, FTO, and MC4R influence how an individual's body responds to satiety signals and metabolic stress

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